Product and Treatment Education – February 17, 2026
Retinoids: Gold Standard in Skincare Science
Retinoids, vitamin A derivatives, revolutionised dermatology as cell-communicating actives that bind nuclear receptors to alter gene expression, boosting cell turnover, collagen, even tone, and texture. Vitamin A deficiency was linked to skin issues like dryness and hyperkeratinisation in the early 1900s; Dr. Albert Kligman advanced this in the 1960s, discovering tretinoin (Retin-A) normalised acne follicles, gaining FDA approval in 1971. In the 1980s, Kligman proved tretinoin repaired photoageing via biopsies showing collagen gains, epidermal thickening, and elastin fixes—proven structural reversal, not masking. Today, retinoids like retinol remain unmatched for acne, pigmentation, and ageing via multi-pathway action.
