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NAD⁺ at Woulfe: Power Cellular Energy, Combat Aging & Menopause Fatigue

NAD⁺ at Woulfe: Power Cellular Energy, Combat Aging & Menopause Fatigue

We often talk about “cellular energy” at Woulfe, because it’s one of the quiet foundations of how you feel day to day. One of the key molecules behind that is NAD (nicotinamide adenine dinucleotide). NAD is involved in how your cells generate energy and how they carry out repair. As we age, NAD levels naturally decline, and periods of high stress, illness, poor sleep or prolonged lifestyle strain may further reduce the bodys resilience.

So who might notice the most benefit from supporting NAD?

If you’re seeing signs of ageing and reduced resilience, NAD matters because it supports mitochondrial energy production (your cell power plants), DNA repair processes, circadian rhythm regulation and aspects of brain and nerve function. In practical terms, when NAD is low, people may report tiredness, brain fog, poorer sleep quality, slower recovery after exercise, or a general sense that their energy and bounce-back isnt what it used to be. Skin can also reflect this shift over time, because skin is a high-demand organ that relies on efficient cellular turnover and repair.

If you’re in perimenopause or menopause, there’s often an overlap between hormonal transition and changes in sleep, energy, mood and cognition. Because NAD naturally declines through midlife, supporting cellular energy during this stage can be a sensible, science-led addition to a broader plan that includes sleep, stress regulation, nutrition, strength training and personalised medical care where needed.

If you’re focused on long-term health maintenance and performance, NAD support is often discussed in the context of optimisation: maintaining strong cellular function so you can think clearly, recover well, train effectively and age with greater resilience. Its not a quick fix, but it can sit alongside the fundamentals that deliver the biggest outcomes: sleep quality, real-food nutrition, movement, stress management and consistent health checks.

A note on the science: NAD is essential to human biology, and research suggests that lower NAD is linked with ageing biology and certain disease processes. Human studies show that some NAD precursors (such as nicotinamide riboside) can increase NAD levels, and early research suggests potential effects on metabolic and inflammatory markers. However, larger, longer-term studies are still needed to confirm clinical outcomes for specific conditions and to clarify who benefits most.

If you’d like, we can talk you through whether NAD support makes sense for you, how it fits with your current routine, and the most sensible foundations first approach to pairing it with skin health, energy, and long-term wellbeing.

February 03, 2026