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NAD⁺ is one of the body’s most important “behind-the-scenes” molecules.

NAD⁺ is one of the body’s most important “behind-the-scenes” molecules.

Its found in every cell, and it helps power energy production while also supporting cellular repair and maintenance. The article you shared makes the case that NAD matters to all of us because it sits at the centre of how we generate energy, respond to stress, and recover. It also states that NAD levels decline with age (it cites an approximate drop of 50% every 20 years), and that lifestyle pressures or illness may accelerate that decline.

 

From there, the article highlights three main groups of people who may be more likely to notice benefits when NAD levels are supported.

 

The first group is people experiencing common “ageing-type” symptoms. These are often not dramatic medical issues, but subtle changes that build gradually and can affect day-to-day quality of life. The article lists brain fog, disrupted sleep, persistent fatigue, reduced cognitive sharpness, decreased skin elasticity, lower athletic performance, and slower recovery from illness. Their proposed explanation is that as NAD availability drops, mitochondrial function can become less efficient, meaning cells may produce energy less effectively. When energy production is compromised, repair and regeneration processes can also slow, and circadian rhythm regulation may become less stable. In practical terms, this can feel like you have less reserve: you can still manage life, but it costs more, and you don’t bounce back as quickly.

 

The second group is people going through peri-menopause and menopause. The article positions NAD support as potentially helpful for the cluster of symptoms many women report during this stage, particularly brain fog, fatigue, and sleep disruption. It notes that menopause typically occurs around age 51 and frames this period as a double shift, where hormonal change and NAD decline can happen in parallel. Their point is not that NAD replaces medical care, but that it may be one supportive tool alongside the fundamentals—sleep, nutrition, stress regulation, movement, and appropriate clinical guidance.

 

The third group is people focused on optimisation and prevention, even if they don’t feel obvious symptoms yet. This is the proactive individual who wants to protect energy, cognitive performance, resilience, and long-term health span. The article suggests that supporting NAD may help with steadier energy, mental sharpness, exercise recovery, immune support, sleep quality, and even cardiovascular function. It also makes a prevention-led argument: rather than waiting until depletion is severe, it may be more effective to support these pathways earlier as part of a long-term strategy.

 

The most useful way to think about this overall message is that NAD is not being framed as a quick fix. Its being positioned as a foundational support molecule for energy and repair, which may be particularly relevant for people noticing fatigue and brain fog, women in the peri-/menopause transition, and those who want to stay well and high-functioning as they age. As always, anyone with persistent or unexplained symptoms should be encouraged to seek appropriate medical assessment, and supplement choices should be matched to the individual, their health history, and any medications they are taking.

February 03, 2026