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Inflammageing- what is it and what can I do to prevent it?

Inflammageing- what is it and what can I do to prevent it?

June 20, 2025

https://podcasts.apple.com/ie/podcast/zoe-science-nutrition/id1611216298?i=1000713559855c



Fatigue, stiffness, pain and brain fog can all be attributed to inflammation in the body , now believed to drive many of the diseases we associate with ageing from dementia to heart disease. 

Symptoms to look for :,

  • Tummy  pain
  • Chest pain
  • Depression, anxiety or mood disorders
  • Fatigue and/or insomnia
  • Fever
  • Frequent infections
  • Gastrointestinal (GI) issues like diarrhea, constipation and acid reflux
  • Joint pain or stiffness
  • Mouth sores
  • Skin rash- rosacea, dermatitis, eczema. 
  • Unexplained weight gain or weight loss
Cellular senescence is one of the hallmarks of ageing and a central pillar in the development and output of each hallmark. Derived from the Latin root senex, meaning an old age - senescence is the end stage in a cell’s life cycle when it stops dividing. It stops dividing, yet refuses to die - the more senescence cells we have the more inflammation we experience Cellular senescence is happening constantly in our bodies. When we’re young and healthy, senescent skin cells are quickly cleared away and replaced with regenerated new cells. But as we get older, more and more senescent cells accumulate. When these cells linger, they secrete biochemical signals that induce chronic inflammation, suppress the immune system, and accelerate aging in neighboring cells. These signals can even inhibit stem cell function, decreasing your tissues’ ability to regenerate.

Hallmarks of ageing : An expanding universe - ScienceDirect
Nuchido Time + is a supplement that addresses cellular ageing. The science is really interesting. 

Leaky gut in systemic inflammation: exploring the link between gastrointestinal disorders and age-related diseases | GeroScience


  • There are some simple steps you can take to help improve your health. The Zoe podcast attached highlights that it is never too late to address the symptoms to bring about change. 
    Exercise daily. Some resistance training, and walking. Yoga and Pilates are also beneficial. 
  • Breath work - Nasal breathing, in particular, can increase the production of nitric oxide, a vasodilator that can help reduce inflammation and congestion. 
  • Practices like box breathing (inhaling for a count of four, holding for four, exhaling for four, holding for four) can promote relaxation and reduce inflammation. 
  • Avoid smoking.
  • Reduce Alcohol intake.
  • Keep hydrated - drink water.
  • De stress - actively bring an awareness to reducing stress . Practice meditation.
  • Sleep - sleep is a nonnegotiable part of a healthy lifestyle. Lack of sleep increases inflammation. 
  • Day light - get out early in day life- this sets your circadian rhythm- a natural body clock which sets your sleep: wake cycle. 
  • Dry  body brush daily to improve lymphatic circulation.
  • Intermittent fasting- aids in lowering inflammation as does cold water swimming seek medical advice before these to prevent any further issues.
  • Vagus Nerve - The vagus nerve , the longest nerve in the body which runs from the  brainstem to major peripheral organs and acts as the main conduit for the body’s inflammatory immune response to disease, bacteria and viruses. For the first time, in 2023 researchers at @TheFeinsteinInstitutes for Medical Research have shown the ability to turn on specific receptors in the vagus nerve, activating the inflammatory reflex. There are lots of devices on the market which claim to activate the vagus nerve. Seek advice to see which works etc . Breath work, singing, gargling, intermittent fasting all aid in activating the vagus nerve. 
Eat an anti- inflammatory diet - by adding more leafy green vegetables, fruits, fatty fish, nuts, olive oil and whole grains to your diet. Be sure to also avoid ultra-processed food and sugar. These foods can trigger inflammation by contributing to visceral fat. This is the bad kind of fat that surrounds your organs. It too drives systemic inflammation. Include polyphenols in your diet . For advice on diet look at The Mediterranean diet. 
A poor diet can also damage the lining of your gut. This damage over time makes the gut walls thin out and become leaky. A leaky gut lets things like food particles, bacteria and toxins pass through the digestive tract in to your blood stream. 


The skin is also susceptible to the negative effects of inflammation as we age. 

Inflammageing , a term now commonly associated with skin ageing- combines  "inflammation" and "ageing ," refers to the chronic , low grade inflammation that occurs with age, and contributes to the visible signs of ageing.This persistent inflammation can accelerate skin ageing , leading to premature wrinkles, loss of elasticity, and other age-related skin changes such as discolouration and or redness. 

Inflammageing and the Skin - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0022202X20322946


In this episode of Zoe pod cast below , immune ageing expert Professor Janet Lord unpacks “Inflammageing”. 

Janet Lord reveals how this invisible inflammation takes hold, how it silently damages the brain, gut, and immune system - and what science says we can do to fight back. Her research has shown that even in your 70s, it's not too late to reverse immune ageing . One small change tomorrow could make a measurable difference.
Professor Janet Lord is a world leading expert in the biology of ageing . She’s published over 200 scientific papers and advised UK health policy. Her work shows how daily habits - especially movement - can reshape the immune system and slow the effects of time.



https://podcasts.apple.com/ie/podcast/zoe-science-nutrition/id1611216298?i=1000713559855c
Inflammageing- what is it and what can I do to prevent it?

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#acne#advice#blog #podcasts#bluelight#discolouration#Glasthule#HEALTH#health #ageingpopulation @worldhealthorganisation#health #wellbeing#inflammation#menopause #skin #skincare #protect#ozone#protect#stress #burnout #sleep #health#vagus nervehydratehydrationProfessorJanetLordSeborrheicDermatitisselfcareSKIN STRESSskin tipsZoepodcast

June 20, 2025

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