Niacinamide works with your skin's natural chemistry to improve overall skin texture by rebuilding a lipid layer, minimising the appearance of pores, and preventing UV damage and inflammation as an antioxidant.
A form of vitamin B3, niacinamide is also believed to reduce redness, discolouration, and even acne, Nicotinamide is an essential water-soluble vitamin, which is not synthesised in the body, meaning we have to eat it to receive its benefits. Additionally, the vitamin has been incorporated into skincare products as our bodies don't produce it on their own. Therefore, if we want to reap the brightening benefits of nicotinamide, it needs to be ingested via supplement or applied topically to the skin.
Nonmelanoma skin cancers, such as basal-cell carcinoma and squamous-cell carcinoma, are common cancers that are caused principally by ultraviolet (UV) radiation. Nicotinamide (vitamin B3) has been shown to have protective effects against damage caused by UV radiation and to reduce the rate of new premalignant actinic keratoses. This study found; Oral nicotinamide was safe and effective in reducing the rates of new nonmelanoma skin cancers and actinic keratoses in high-risk patients. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention | NEJM
The B3 mentioned in the name of SkinCeuticals Metacell Renewal B3 is niacinamide, which proves how well it plays with other ingredients in this multipurpose emulsion. This lightweight lotion combines five percent niacinamide, a tripeptide complex, and glycerine to deliver hydration without feeling heavy or leaving the skin feeling greasy.
"Peptides are short chains of amino acids," says New York City-based board-certified dermatologist Cindy Bae, M.D., "with amino acids being the smallest unit of a protein." And protein — in the form of elastin, keratin, and, mostly, collagen — is what gives skin its structure and resilience.
Cosmetics | Free Full-Text | Skin Regenerative and Anti-Cancer Actions of Copper Peptides
https://www.mdpi.com/2079-9284/5/2/29/html
What Is the Skin's Moisture Barrier? Plus, How to Avoid Damaging It | Allure
https://www.allure.com/story/what-is-moisture-barrier-skin-care
You'll typically find peptides in leave-on products — think moisturizers and serums versus cleansers. Most peptide-enriched products are touted as such on the front of the bottle, but you can check the ingredient list for words like "dipeptide," "tripeptide," and "hexapeptide" if you’re not sure. Many formulations utilize multiple forms of peptides in order to maximize the collagen-boosting benefits, or pair peptides with other ingredients that help support a healthy skin barrier. And the good news is, no matter your price range, there are plenty of options on the market.
"The Sandwich Technique." This involves applying a layer of cream to the skin, using your retinol of choice on top of that, and then slathering on even more moisturizer to lock it all in. "Studies have shown that this base layer of moisturizer does not dilute or reduce the efficacy of the retinoid, but instead helps with tolerability
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/
https://www.allure.com/story/retinols-sensitive-skin
Does Sunscreen With SPF 100 Give You 100% Protection Against the Sun? | Allure
https://www.allure.com/story/is-higher-spf-sunscreen-better-study
