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January 26, 2021 3 min read

SkinCeuticals Silymarin CF antioxidant serum is unique, in that it is the first of its kind clinically-proven for use on oily and blemish-prone skin

This latest innovation is the pioneering, next-generation Silymarin CF: its first ever vitamin C serum for oily, blemish-prone skin. As with C E Ferulic and Phloretin CF, this potent antioxidant is designed to reinforce the skin’s natural protection against free radical damage with a unique combination of active ingredients including 15% pure vitamin C (L-ascorbic acid), 0.5% ferulic acid, 0.5% salicylic acid and 0.5% silymarin.

Why is this important?

Growing research has shown a causative link between the formation of blemishes and oil oxidation. Oxidative stress such as lipid peroxidation can contribute to inflammation in the skin which diminishes antioxidants, creating the ideal environment for bacteria to grow. SkinCeuticals’ research shows that those with blemish-prone skin actually have lower levels of antioxidants and higher levels of sebum production. This, in turn, leaves the skin at greater risk of damage but by applying antioxidants topically, lipid peroxidation is prevented, and the formation of blemishes is decreased.

Silymarin: the antioxidant answer for blemish-prone skin

Sourced from milk thistle, Silymarin is known for its detoxification properties that are believed to have a number of holistic benefits such as supporting healthy liver function. When applied topically to the skin, it’s clinically proven to provide protection against environmental damage and free radicals while improving visible signs of ageing. Most significantly, its ability to significantly reduce oil oxidation makes it incredibly effective at treating oil and imperfections.

During the process of creating Silymarin CF, SkinCeuticals tested a number of antioxidants to see how well they prevented lipid peroxidation. Vitamin E, for example, is considered one of the most effective ways of preventing lipid peroxidation in the skin, but its oily and viscous texture makes it more suited to drier skin types. Silymarin, on the other hand, was originally recognised by Dr Pinnell for its antioxidant potential, ability to reduce oil oxidation and lightweight texture.

Armed with this knowledge, SkinCeuticals secured a patent on its use to combat photo-ageing and skin inflammation.

Clinical results

In a 12-week study conducted in Brazil in 2020 with 60 women, 15% of participants saw a reduction in oiliness and 24% saw an improvement in the appearance of fine lines and wrinkles. Additionally, in a study in China undertaken in 2020, 35 of the subjects studied saw a 76% reduction in oil oxidation. As a result, participants found their skin texture and clarity was also improved, and the appearance of pores and blemishes was also reduced.

Clinical study 35 subjects (China 2020)

• Reduces oil oxidation by up to 76%

• Reduces the appearance of pores

• Reduces the appearance of blemishes

• Reduces excess sebum/oil by up to 15%

12-week clinical study, 60 women (Brazil 2020)

• Improves appearance of fine lines and wrinkles by up to 24%

• Improves skin texture

• Improves skin clarity

8-week clinical study, 55 women (US 2019)

• Refines skin texture and improves skin tone

• Reduces oiliness by up to 15%

A complete antioxidant range

The SkinCeuticals antioxidant range now comprises of four vitamin C serums: C E Ferulic for dry and mature skin, Phloretin CF for hyperpigmented skin, and Silymarin CF for oily and blemish-prone skin and Serum 10 is entry level of Vitamin C . This potent range of medical grade skin care products will allow you address all the issues associated with your specific skin needs. 

Silymarin CF



CE Ferulic


Phloretin CF 



Serum 10 


Limited Edition Kits


Radiance promotion Gift set



Illuminate Promotion kit 



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