January 14, 2021 2 min read

Essential fatty acids, Ceramides and Cholesterol are all naturally occurring lipids in the correct ratio in healthy skin. Lipids are the good fats in your skin that make it look healthy and young; as you age, your skin loses them, causing dullness, dryness, and wrinkles. These healthy fats play a critical role in maintaining a healthy functioning skin barrier. The skin barrier is Crucial for this skin barrier function is the lipid matrix in the outermost layer of the skin, the stratum corneum.

Two of its functions are to;

  1. prevents excessive water loss through the epidermis

  2. to prevent pathogens etc from the environment penetrating into the viable epidermal and dermal layers and thereby provoke an immune response.

They also aid in the skins natural repair process.

Healthy, youthful skin has an abundance of these lipids. As we age, lipid production declines, this is made worse when the skin has been damaged repeatedly over the years due to excess UV and environmental damage. This can lead to dry, rough, red, irritated skin. Along with a visible loss of facial fullness.

A compromised skin barrier lacking in the correct ratio of lipids is seen as the primary cause of acne, acne rosacea and atopic dermatitis etc.

Essential fatty acids abundant in youthful, healthy skin help to maintain the skins lipid balance.

Cholesterol; Crucial for this skin barrier function is the lipid matrix in the outermost layer of the skin, the stratum corneum.

Two of its functions are

(1) to prevent excessive water loss through the epidermis

(2) to prevent pathogen’s and damage penetrating through the fragile epidermal and dermal layers and thereby provoking an immune response.

Ceramides; Ceramide deficiency is seen as dry skin.  Ceramides are added to skincare to boost hydration levels and increase barrier function.

Atopic dermatitis, acne, acne rosacea is all seen as a result of a compromised skin barrier.


The ratio of lipids is important – studies say that a ratio of 2:4:2 cholesterol-dominant is the optimal to help restore skin’s external barrier and support natural self-repair. Scientists at SkinCeuticals found the exact ratio of lipids present in young skin and replicated it in this cream: 2 %ceramides, 4 % cholesterol, and 2 %fatty acids. With this ratio, the moisturiser mimics normal, young skin as accurately as possible. They have patented it -  U.S. Patent No. 10137073A  anti-ageing cream to refill cellular lipids and nourish dry skin and called it.


Triple Lipid Restore 2:4:2.




CE Ferulic features a synergistic antioxidant combination of 15% pure vitamin C This form of vitamin E neutralises free radicals and replenishes skin lipids. This vitamin C serum is recognised as the gold standard in vitamin c antioxidant serums. Used daily in the morning under a good quality broad spectrum SPF it multiplies the environmental protection by 4 x times. 

Shopnow https://www.nualawoulfe.ie/collections/skinceuticals/products/skinceuticals-c-e-ferulic%C2%AE-30ml

Ultra50 https://www.nualawoulfe.ie/collections/skinceuticals/products/skinceuticals-ultra-facial-defense-spf-50-very-high-protection-30ml

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